Sligo-based Rescue 118 were tasked to a multi-agency operation on Inishbofin on Friday evening.
Clifden RNLI launched both their lifeboats after receiving reports of a man who has sustained injuries on the island.
Upon arrival at southwest of the Island, the casualty was found to have a serious leg injury and was in significant pain.
The lifeboat crew carried out a full casualty care assessment, they were able to assist with pain management and make him more comfortable for transport.
Rescue 118 arrived on scene and the lifeboat crew worked with Coast Guard colleagues to safely winch the casualty on board the aircraft and onwards to Mayo University Hospital.
The public are being reminded that if they see someone in difficulty in the water dial 999/112 and ask for the Coast Guard.
