The rate of Covid-19 in the Buncrana local electoral area in Donegal is over seven times the national average.
Its 14-day incidence rate was 881 per 100,000 people on Monday - the highest in the country.
Dungarvan in Waterford is the next highest, at 771.
Carndonagh, also in Donegal, is the third worst, at 625.
Ireland has the fourth-highest incidence rate of Covid-19 in the EU - with only Cyprus, Portugal, and Spain faring worse.
The Republic's 14-day rate is 121 per 100,000 people, with 534 new cases confirmed yesterday.
627 new cases were reported in the North yesterday - the highest since late January.
Donegal GP Denis McCauley, from the Irish Medical Organisation, fears the Republic's rate could increase six-fold in the coming weeks.
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