Sitting Sinn Féin MEP Chris MacManus is in danger of losing his seat in Europe.
It's after he received just 29,427 first preferences after the first count.
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Meanwhile Fine Gael are set to take two seats in the Midlands Northwest European constituency.
Nina Carberry and Maria Walsh got over 145,000 first preference votes between them.
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Luke Ming Flanagan topped the poll, and is closely followed by Fianna Fail's Barry Cowen, while former RTE correspondent Ciarán Mullooly is in poll position to take the fifth and final seat.
